Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL

Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL

The purpose of this study was to investigate effect of bioadhesion on the initial in vitro buoyancy behaviour of effervescent matrix tablets of ciprofloxacin HCl (CIPRO). Tablets were prepared by direct compression using HPMC K4M and Carbopol 971P as hydrophilic-controlled release polymers, sodium b...

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Bibliographic Details
Main Authors: Jeetendra Singh Negi, Abhinav Trivedi, Praveen Khanduri, Vandana Negi, Nikhil Kasliwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Bioadhesion
effervescent matrix tablets
gastroretention
modified buoyancy lag time
swelling agents
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2011;volume=2;issue=2;spage=121;epage=127;aulast=Negi

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