Stem cell models of Alzheimer’s disease: progress and challenges
Abstract A major challenge to our understanding of the molecular mechanisms of Alzheimer’s disease (AD) has been the lack of physiologically relevant in vitro models which capture the precise patient genome, in the cell type of interest, with physiological expression levels of the gene(s) of interes...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-06-01
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Series: | Alzheimer’s Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13195-017-0268-4 |