Oral Antioxidant Vitamins and Magnesium Limit Noise-Induced Hearing Loss by Promoting Sensory Hair Cell Survival: Role of Antioxidant Enzymes and Apoptosis Genes

Oral Antioxidant Vitamins and Magnesium Limit Noise-Induced Hearing Loss by Promoting Sensory Hair Cell Survival: Role of Antioxidant Enzymes and Apoptosis Genes

Noise induces oxidative stress in the cochlea followed by sensory cell death and hearing loss. The proof of principle that injections of antioxidant vitamins and Mg<sup>2+</sup> prevent noise-induced hearing loss (NIHL) has been established. However, effectiveness of oral administration...

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Bibliographic Details
Main Authors: Juan C. Alvarado, Verónica Fuentes-Santamaría, Pedro Melgar-Rojas, María C. Gabaldón-Ull, José J. Cabanes-Sanchis, José M. Juiz
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
auditory
deafness
acoustic trauma
hair cells
antioxidant
otoprotection
Online Access:https://www.mdpi.com/2076-3921/9/12/1177

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