Neuroligin 1 Modulates Striatal Glutamatergic Neurotransmission in a Pathway and NMDAR Subunit-Specific Manner

Neuroligin 1 Modulates Striatal Glutamatergic Neurotransmission in a Pathway and NMDAR Subunit-Specific Manner

ABSTRACTTogether with its presynaptic partner Neurexin 1 (Nxn1), Neuroligin 1 (NL1) participates in synapse specification and synapse maintenance. We and others have shown that NL1 can also modulate glutamatergic synaptic function in the central nervous system of rodent models. These molecular/cellu...

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Bibliographic Details
Main Authors: Felipe eEspinosa, Zhong eXuan, Shunan eLiu, Craig M Powell
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Synaptic Transmission
Striatum
Autism Spectrum Disorders
mEPSC
GluN2A
GluN2B
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2015.00011/full

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