Comparison of Indices of Insulin Resistance and Islet Beta-Cell Dysfunction across Rat Models of Diabetes Mellitus Induced by Modified Diets or Streptozotocin

Comparison of Indices of Insulin Resistance and Islet Beta-Cell Dysfunction across Rat Models of Diabetes Mellitus Induced by Modified Diets or Streptozotocin

Background: Induction of insulin resistance in rodents involves the use of Streptozotocin (STZ) or diets high in sucrose, fat or fructose; but the relative degrees of insulin resistance induced by each of these approaches are unclear. Aim and Objectives: We therefore compared the degree to whic...

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Bibliographic Details
Main Authors: Oluwole Busayo Akinola, Sikiru Abayomi Biliaminu, Emmanuel Olusola Yawson, Michael Oluwatosin Gabriel
Format: Article
Language:English
Published: Krishna Institute of Medical Sciences University 2018-04-01
Series:Journal of Krishna Institute of Medical Sciences University
Subjects:
Insulin Resistance
β Cell
High Fat Diet
Wistar rats
Streptozotocin
Online Access:http://www.jkimsu.com/jkimsu-vol7no2/JKIMSU,%20Vol.%207,%20No.%202,%20April-June%202018%20Page%201-9.pdf

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