COX-2 Forms Regulatory Loop with YAP to Promote Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells

COX-2 Forms Regulatory Loop with YAP to Promote Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells

COX-2 and YAP are shown to be highly associated with hepatocellular carcinoma (HCC) and frequently upregulated during tumor formation. However, despite their importance, whether there is a mutual interaction between COX-2 and YAP and how they regulate each other are not clear. In this paper, we show...

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Bibliographic Details
Main Authors: Guanglin Xu, Ying Wang, Weijie Li, Yuanyuan Cao, Jinling Xu, Ziwei Hu, Yaping Hao, Li Hu, Yawen Sun
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861730427X

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