Possible Role for Interleukin-5 in Asthma
Background: Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5. Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera sam...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine University of Baghdad
2007-01-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1473 |
| Summary: | Background: Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5.
Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method.
Results & Conclusions: There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls (P< 0.001). We conclude that this cytokine may play the major
role in asthmatic attack & it may be a good marker for the disease.
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| ISSN: | 0041-9419 2410-8057 |