Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies

Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies

Congenital heart block (CHB) is a rare disorder that may be associated with a high morbidity and even mortality, with a risk of death both in utero and during infancy. Women with serum titres of anti-Ro and/or anti-La antibodies carry a risk of CHB of 1–5% in their offspring, with a recurrence risk...

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Main Authors: E. Thornton, L. Tripathi, S. Shebani, I. Bruce, L. Byrd
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2017/8352320
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spelling doaj-d1bd003e7b6e4a21a4e32b2f4dc6e1cb2020-11-24T23:00:42ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66842090-66922017-01-01201710.1155/2017/83523208352320Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro AntibodiesE. Thornton0L. Tripathi1S. Shebani2I. Bruce3L. Byrd4ST1 Obstetrics and Gynaecology, Royal Bolton Hospital, Bolton, UKNorth Manchester General Hospital, Manchester, UKGlenfield Hospital, Leicester, UKDepartment of Rheumatology, Manchester Royal Infirmary, Manchester, UKSt Mary’s Hospital, Manchester, UKCongenital heart block (CHB) is a rare disorder that may be associated with a high morbidity and even mortality, with a risk of death both in utero and during infancy. Women with serum titres of anti-Ro and/or anti-La antibodies carry a risk of CHB of 1–5% in their offspring, with a recurrence risk of approximately 20%. We present a case of a 36-year-old female with a pregnancy complicated by congenital heart block. Autoimmune profiling at booking showed she was positive for lupus anticoagulant and anti-Ro antibodies. A fetal echocardiogram at 21 + 3 showed complete heart block. She was monitored throughout the remainder of her pregnancy with serial growth scans, cardiovascular profiling, and BPP scoring. She had a normal vaginal delivery at term to a female infant.http://dx.doi.org/10.1155/2017/8352320
collection DOAJ
language English
format Article
sources DOAJ
author E. Thornton
L. Tripathi
S. Shebani
I. Bruce
L. Byrd
spellingShingle E. Thornton
L. Tripathi
S. Shebani
I. Bruce
L. Byrd
Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies
Case Reports in Obstetrics and Gynecology
author_facet E. Thornton
L. Tripathi
S. Shebani
I. Bruce
L. Byrd
author_sort E. Thornton
title Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies
title_short Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies
title_full Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies
title_fullStr Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies
title_full_unstemmed Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies
title_sort facilitation of vaginal delivery in an infant with complete heart block secondary to maternal anti-ro antibodies
publisher Hindawi Limited
series Case Reports in Obstetrics and Gynecology
issn 2090-6684
2090-6692
publishDate 2017-01-01
description Congenital heart block (CHB) is a rare disorder that may be associated with a high morbidity and even mortality, with a risk of death both in utero and during infancy. Women with serum titres of anti-Ro and/or anti-La antibodies carry a risk of CHB of 1–5% in their offspring, with a recurrence risk of approximately 20%. We present a case of a 36-year-old female with a pregnancy complicated by congenital heart block. Autoimmune profiling at booking showed she was positive for lupus anticoagulant and anti-Ro antibodies. A fetal echocardiogram at 21 + 3 showed complete heart block. She was monitored throughout the remainder of her pregnancy with serial growth scans, cardiovascular profiling, and BPP scoring. She had a normal vaginal delivery at term to a female infant.
url http://dx.doi.org/10.1155/2017/8352320
work_keys_str_mv AT ethornton facilitationofvaginaldeliveryinaninfantwithcompleteheartblocksecondarytomaternalantiroantibodies
AT ltripathi facilitationofvaginaldeliveryinaninfantwithcompleteheartblocksecondarytomaternalantiroantibodies
AT sshebani facilitationofvaginaldeliveryinaninfantwithcompleteheartblocksecondarytomaternalantiroantibodies
AT ibruce facilitationofvaginaldeliveryinaninfantwithcompleteheartblocksecondarytomaternalantiroantibodies
AT lbyrd facilitationofvaginaldeliveryinaninfantwithcompleteheartblocksecondarytomaternalantiroantibodies
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