Human Leukocyte Antigens and Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma: Old Associations Offer New Clues into the Role of Immunity in Infection-Associated Cancers

Human Leukocyte Antigens and Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma: Old Associations Offer New Clues into the Role of Immunity in Infection-Associated Cancers

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated tumor. In addition to EBV, host genetic factors are believed to be important determinants of NPC risk. Of all genes studies to date, human leukocyte antigen (HLA) genes have shown the most consistent evidence for association...

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Bibliographic Details
Main Authors: Wen-Hui eSu, Allan eHildesheim, Yu-Sun eChang
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Oncology
Subjects:
HLA Antigens
ebv
GWAS (genome-wide association study)
nasopharyngeal carcinoma
infection associated cancers
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00299/full

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