Reduction of dynamical biochemical reactions networks incomputational biology

Reduction of dynamical biochemical reactions networks incomputational biology

Biochemical networks are used in computational biology, tomodel mechanistic details of systems involved in cell signaling, metabolism,and regulation of gene expression. Parametric and structural uncertainty, as well ascombinatorial explosion are strong obstacles against analyzing the dynamics of lar...

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Bibliographic Details
Main Authors: Ovidiu eRadulescu, Alexander N. eGorban, Andrei eZinovyev, Vincent eNoel
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Genetics
Subjects:
Computational Biology
Dynamical Networks
model reduction
quasi-equilibrium approximation
quasi-steady state approximation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00131/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00131/full

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