Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA

Summary: Human Fc receptor-like 3 (FCRL3) is an orphan receptor expressed by lymphocytes, including regulatory T cells. FCRL3 is implicated in several autoimmune diseases; however, its function on regulatory T cells is unknown. We discovered that FCRL3 stimulation of regulatory T cells inhibited the...

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Bibliographic Details
Main Authors: Stuti Agarwal, Zachary Kraus, Jessica Dement-Brown, Oyeleye Alabi, Kyle Starost, Mate Tolnay
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719317644