Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling

Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling

Glucosamine impairs hepatic apolipoprotein B100 (apoB100) production by inducing endoplasmic reticulum (ER) stress and enhancing cotranslational and posttranslational apoB100 degradation (Qiu, W., R. K. Avramoglu, A. C. Rutledge, J. Tsai, and K. Adeli. Mechanisms of glucosamine-induced suppression o...

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Bibliographic Details
Main Authors: Wei Qiu, Qiaozhu Su, Angela C. Rutledge, Jing Zhang, Khosrow Adeli
Format: Article
Language:English
Published: Elsevier 2009-09-01
Series:Journal of Lipid Research
Subjects:
α-subunit of eukaryotic initiation factor 2
glucose-regulated protein 78
degradation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307331

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http://www.sciencedirect.com/science/article/pii/S0022227520307331

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