Plant Sterol Ester of α-Linolenic Acid Attenuates Nonalcoholic Fatty Liver Disease by Rescuing the Adaption to Endoplasmic Reticulum Stress and Enhancing Mitochondrial Biogenesis

Plant Sterol Ester of α-Linolenic Acid Attenuates Nonalcoholic Fatty Liver Disease by Rescuing the Adaption to Endoplasmic Reticulum Stress and Enhancing Mitochondrial Biogenesis

Nonalcoholic fatty liver disease (NAFLD) is becoming more common in the world and is presenting a great challenge concerning prevention and treatment. Plant sterol ester of α-linolenic acid (PS-ALA) has a potential benefit to NAFLD. To examine the effect of PS-ALA on NAFLD, C57BL/6J mice were given...

Full description

Bibliographic Details
Main Authors:	Hao Han, Yan Guo, Xiaoyu Li, Dongxing Shi, Tingli Xue, Linqi Wang, Yanyan Li, Mingming Zheng
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2019/8294141

Similar Items

Emerging role of the endoplasmic reticulum in peroxisome biogenesis
by: Gaurav eAgrawal, et al.
Published: (2013-10-01)

An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
by: Sarah O’Keefe, et al.
Published: (2021-07-01)

Flaxseed Oil Containing α-Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice
by: Hao Han, et al.
Published: (2015-01-01)

Endoplasmic reticulum stress response in nonalcoholic fatty liver disease
by: Arushana Ali, et al.
Published: (2018-01-01)

Synthesis and biological evaluation of novel inhibitors of protein biogenesis at the endoplasmic reticulum
by: Williams, Helen Mary
Published: (2012)

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.
by: Evan Quon, et al.
Published: (2018-05-01)

Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway
by: Xiaobo Gao, et al.
Published: (2018-11-01)

Role of endoplasmic reticulum stress in pathogenesis of nonalcoholic fatty liver disease
by: WANG Jian
Published: (2014-11-01)

Correction to: Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway
by: Xiaobo Gao, et al.
Published: (2019-08-01)

Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis.
by: Xi Chen, et al.
Published: (2012-01-01)

α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes
by: Shi Hongyang, et al.
Published: (2011-05-01)

Mutual interaction between endoplasmic reticulum and mitochondria in nonalcoholic fatty liver disease
by: Jin Wang, et al.
Published: (2020-04-01)

Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes
by: Dong Lei, et al.
Published: (2011-07-01)

Functional Dissection of FKBP38 in the Biogenesis of Cystic Fibrosis Transmembrane Conductance Regulator in the Endoplasmic Reticulum
by: Banasavadi-Siddegowda, Yeshavanth Kumar
Published: (2011)

Fluvoxamine attenuated endoplasmic reticulum stress-induced leptin resistance
by: Toru eHosoi, et al.
Published: (2012-01-01)

Evaluation of the role of the Endoplasmic Reticulum-Golgi transit in the biogenesis of peroxisomal membrane proteins in wild type and peroxisome biogenesis mutant CHO cells
by: ANDRÉS TORO, et al.
Published: (2007-01-01)

Endoplasmic Reticulum
Published: (2019)

Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model
by: Graziella Rodrigues, et al.
Published: (2019-01-01)

Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury
by: Honglei Guo, et al.
Published: (2016-01-01)

Attenuation of endoplasmic reticulum stress as a treatment strategy against ischemia/reperfusion injury
by: Chih-Li Lin
Published: (2015-01-01)

Polyamine Depletion Attenuates Isoproterenol-Induced Hypertrophy and Endoplasmic Reticulum Stress in Cardiomyocytes
by: Yan Lin, et al.
Published: (2014-10-01)

Endoplasmic Reticulum Stress is Involved in DFMO Attenuating Isoproterenol-Induced Cardiac Hypertrophy in Rats
by: Yan Lin, et al.
Published: (2016-04-01)

Naringin attenuates cerebral ischemia-reperfusion injury in rats by inhibiting endoplasmic reticulum stress
by: Wang Li, et al.
Published: (2021-05-01)

Dexmedetomidine Attenuates Myocardial Ischemia-Reperfusion Injury in Diabetes Mellitus by Inhibiting Endoplasmic Reticulum Stress
by: Jinjie Li, et al.
Published: (2019-01-01)

Updates on Endoplasmic Reticulum
Published: (2023)

Flavivirus Replication Organelle Biogenesis in the Endoplasmic Reticulum: Comparison with Other Single-Stranded Positive-Sense RNA Viruses
by: Masashi Arakawa, et al.
Published: (2019-05-01)

Rescue of ATXN3 neuronal toxicity in Caenorhabditis elegans by chemical modification of endoplasmic reticulum stress
by: Yasmin Fardghassemi, et al.
Published: (2017-12-01)

Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid
by: Zhou F, et al.
Published: (2017-03-01)

Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
by: Toru Hosoi, et al.
Published: (2014-03-01)

Glutamine treatment attenuates endoplasmic reticulum stress and apoptosis in TNBS-induced colitis.
by: Irene Crespo, et al.
Published: (2012-01-01)

Selenate Prevents Adipogenesis through Induction of Selenoprotein S and Attenuation of Endoplasmic Reticulum Stress
by: Choon Young Kim, et al.
Published: (2018-11-01)

Zinc Attenuates the Cytotoxicity of Some Stimuli by Reducing Endoplasmic Reticulum Stress in Hepatocytes
by: Masashi Kusanaga, et al.
Published: (2019-05-01)

Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence[S]
by: Masaki Igarashi, et al.
Published: (2010-02-01)

Endoplasmic Reticulum Stress and Lipid Metabolism
by: Huiping Zhou, et al.
Published: (2012-01-01)

PGC-1α Controls Mitochondrial Biogenesis in Drug-Resistant Colorectal Cancer Cells by Regulating Endoplasmic Reticulum Stress
by: Chul Won Yun, et al.
Published: (2019-04-01)

Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis
by: Qingling Yang, et al.
Published: (2019-07-01)

A standardized notoginseng extract exerts cardioprotection by attenuating apoptosis under endoplasmic reticulum stress conditions
by: Li-Chao Wang, et al.
Published: (2015-06-01)

Quantification of the plant endoplasmic reticulum
by: Bouchekhima, Abdnacer
Published: (2009)

Catestatin improves insulin sensitivity by attenuating endoplasmic reticulum stress: In vivo and in silico validation
by: Abhijit Dasgupta, et al.
Published: (2020-01-01)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
by: Seok-Woo Hong, et al.
Published: (2018-03-01)