Arachidonic acid cytochrome P450 epoxygenase pathway

Arachidonic acid cytochrome P450 epoxygenase pathway

Cytochrome P450 (CYP) epoxygenases convert arachidonic acid to four epoxyeicosatrienoic acid (EET) regioisomers, 5,6-, 8,9-, 11,12-, and 14,15-EET, that function as autacrine and paracrine mediators. EETs produce vascular relaxation by activating smooth muscle large-conductance Ca2+-activated K+ cha...

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Bibliographic Details
Main Author:	Arthur A. Spector
Format:	Article
Language:	English
Published:	Elsevier 2009-01-01
Series:	Journal of Lipid Research
Subjects:	dihydroxyeicosatrienoic acid eicosapentaenoic acid endocannabinoids epoxyeicosatrienoic acid 2-epoxyeicosatrienoylglycerol fatty acid binding protein
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520305861

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