Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity
The last decades of Nobel prize-honored research have unequivocally proven a key role of dendritic cells (DCs) at controlling both T cell immunity and tolerance. A tight balance between these opposing DC functions ensures immune homeostasis and host integrity. Its perturbation could explain patholog...
Main Authors: | Christian Thomas Mayer, Luciana eBerod, Tim D. Sparwasser |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-07-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00183/full |
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