Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity

The last decades of Nobel prize-honored research have unequivocally proven a key role of dendritic cells (DCs) at controlling both T cell immunity and tolerance. A tight balance between these opposing DC functions ensures immune homeostasis and host integrity. Its perturbation could explain patholog...

Full description

Bibliographic Details
Main Authors: Christian Thomas Mayer, Luciana eBerod, Tim D. Sparwasser
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00183/full