The Sub-Nuclear Localization of RNA-Binding Proteins in KSHV-Infected Cells

The Sub-Nuclear Localization of RNA-Binding Proteins in KSHV-Infected Cells

RNA-binding proteins, particularly splicing factors, localize to sub-nuclear domains termed nuclear speckles. During certain viral infections, as the nucleus fills up with replicating virus compartments, host cell chromatin distribution changes, ending up condensed at the nuclear periphery. In this...

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Bibliographic Details
Main Authors: Ella Alkalay, Chen Gam Ze Letova Refael, Irit Shoval, Noa Kinor, Ronit Sarid, Yaron Shav-Tal
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
KHSV
nuclear speckles
SRSF2
nuclear structure
RNA
Online Access:https://www.mdpi.com/2073-4409/9/9/1958

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