Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma

Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma

<p>Abstract</p> <p>Head & Neck Cancer (HNC) is one of the most common malignancies worldwide and among oral neoplasias about 90-92% are squamous cell carcinomas (OSCC). Alcohol and tobacco consumption have been recognized as the main risk factors for development of OSCC. Howeve...

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Main Authors: Bertolus Chloé, Goudot Patrick, Gessain Antoine, Berthet Nicolas
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Infectious Agents and Cancer
Online Access:http://www.infectagentscancer.com/content/7/1/13
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spelling doaj-d1938fbcddf5496283da1d6c38b273252020-11-24T21:47:08ZengBMCInfectious Agents and Cancer1750-93782012-05-01711310.1186/1750-9378-7-13Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinomaBertolus ChloéGoudot PatrickGessain AntoineBerthet Nicolas<p>Abstract</p> <p>Head & Neck Cancer (HNC) is one of the most common malignancies worldwide and among oral neoplasias about 90-92% are squamous cell carcinomas (OSCC). Alcohol and tobacco consumption have been recognized as the main risk factors for development of OSCC. However, 10 to 20% of patients suffering from OSCC have no history of use of these substances. Clinico-pathological evidence suggests that we are dealing with virally-induced cancers, and that HPV should not be a relevant candidate. A systematic search of HPV in OSCC has no real relevance in current clinical practice even although it is still relevant in organized research protocols. Further studies are ongoing, with the aim of identifying other infectious agents, including viruses, in OSCC.</p> http://www.infectagentscancer.com/content/7/1/13
collection DOAJ
language English
format Article
sources DOAJ
author Bertolus Chloé
Goudot Patrick
Gessain Antoine
Berthet Nicolas
spellingShingle Bertolus Chloé
Goudot Patrick
Gessain Antoine
Berthet Nicolas
Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma
Infectious Agents and Cancer
author_facet Bertolus Chloé
Goudot Patrick
Gessain Antoine
Berthet Nicolas
author_sort Bertolus Chloé
title Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma
title_short Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma
title_full Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma
title_fullStr Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma
title_full_unstemmed Clinical relevance of systematic human papillomavirus (HPV) diagnosis in oral squamous cell carcinoma
title_sort clinical relevance of systematic human papillomavirus (hpv) diagnosis in oral squamous cell carcinoma
publisher BMC
series Infectious Agents and Cancer
issn 1750-9378
publishDate 2012-05-01
description <p>Abstract</p> <p>Head & Neck Cancer (HNC) is one of the most common malignancies worldwide and among oral neoplasias about 90-92% are squamous cell carcinomas (OSCC). Alcohol and tobacco consumption have been recognized as the main risk factors for development of OSCC. However, 10 to 20% of patients suffering from OSCC have no history of use of these substances. Clinico-pathological evidence suggests that we are dealing with virally-induced cancers, and that HPV should not be a relevant candidate. A systematic search of HPV in OSCC has no real relevance in current clinical practice even although it is still relevant in organized research protocols. Further studies are ongoing, with the aim of identifying other infectious agents, including viruses, in OSCC.</p>
url http://www.infectagentscancer.com/content/7/1/13
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AT gessainantoine clinicalrelevanceofsystematichumanpapillomavirushpvdiagnosisinoralsquamouscellcarcinoma
AT berthetnicolas clinicalrelevanceofsystematichumanpapillomavirushpvdiagnosisinoralsquamouscellcarcinoma
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