Preparation and Characterization of a Dry Powder Inhaler Composed of PLGA Large Porous Particles Encapsulating Gentamicin Sulfate

Preparation and Characterization of a Dry Powder Inhaler Composed of PLGA Large Porous Particles Encapsulating Gentamicin Sulfate

Purpose: Direct delivery of aminoglycosides to the lungs was under extensive evaluations during the last decades. Because of large particle size, low density and porous structure, large porous particles (LPPs) are versatile carriers for this purpose. In this study, poly (lactic-co-glycolic acid) (PL...

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Bibliographic Details
Main Authors: Farideh Shiehzadeh, Mohsen Tafaghodi, Majid Laal-Dehghani, Faezeh Mashhoori, Bibi Sedigheh Fazly Bazzaz, Mohsen Imenshahidi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Aminoglycosides
Drug delivery systems
Dry powder inhalers
Gentamicin sulfate
Large porous particles
Lung
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-25397

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