An all-trans-retinal-binding opsin peropsin as a potential dark-active and light-inactivated G protein-coupled receptor
Abstract Peropsin or retinal pigment epithelium-derived rhodopsin homolog, found in many animals, belongs to the opsin family. Most opsins bind to 11-cis-retinal as a chromophore and act as light-activated G protein-coupled receptors. Some peropsins, however, bind all-trans-retinal and isomerise it...
Main Authors: | Takashi Nagata, Mitsumasa Koyanagi, Robert Lucas, Akihisa Terakita |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-21946-1 |
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