Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs

Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs

Approximately 80% of adults are infected with a member of the herpesviridae family. Herpesviruses establish life-long latent infections within neurons, which may reactivate into lytic infections due to stress or immune suppression. There are nine human herpesviruses (HHV) posing health concerns from...

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Bibliographic Details
Main Authors:	Lana F. Thaljeh, J. Ainsley Rothschild, Misagh Naderi, Lyndon M. Coghill, Jeremy M. Brown, Michal Brylinski
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Biomolecules
Subjects:	herpesviruses herpes simplex virus 1 hhv-1 dna packaging terminase pul15 dna packaging motor
Online Access:	https://www.mdpi.com/2218-273X/9/10/603

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