A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells

A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells

Abstract Background Autophagy is a highly regulated biological process that mediates the degradation of intracellular components. It is required for tumor cell metabolism and homeostasis. Yin-Yang 1 (YY1) has been reported to be involved in autophagy in several carcinomas. However, its role in autop...

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Bibliographic Details
Main Authors: Chuang Yang, Jing-Jing Zhang, Yun-Peng Peng, Yi Zhu, Ling-Di Yin, Ji-Shu Wei, Wen-Tao Gao, Kui-Rong Jiang, Yi Miao
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Translational Medicine
Subjects:
Autophagy
YY1
miR-30a
Pancreatic cancer
Online Access:http://link.springer.com/article/10.1186/s12967-017-1308-3

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