3D particle averaging and detection of macromolecular symmetry in localization microscopy
Adaptation of current algorithms to 3D SMLM data is currently problematic. Here the authors report a method that increases the signal-to-noise ratio and resolution of 3D single particle analysis in localization microscopy and enables determination of the symmetry groups of macromolecular complexes.
Bibliographic Details
Main Authors: |
Hamidreza Heydarian,
Maarten Joosten,
Adrian Przybylski,
Florian Schueder,
Ralf Jungmann,
Ben van Werkhoven,
Jan Keller-Findeisen,
Jonas Ries,
Sjoerd Stallinga,
Mark Bates,
Bernd Rieger |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-021-22006-5
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