Cytoprotective Properties of Carnosine against Isoniazid-Induced Toxicity in Primary Cultured Rat Hepatocytes

Cytoprotective Properties of Carnosine against Isoniazid-Induced Toxicity in Primary Cultured Rat Hepatocytes

Background: Drug-induced liver injury is a critical clinical complication. Hence, finding new and safe protective agents with potential clinical application is of value. Isoniazid (INH) is an antituberculosis agent widely used against Mycobacterium tuberculosis infection in human. On the other hand,...

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Bibliographic Details
Main Authors: Aziz Eftekhari, Reza Heidari, Elham Ahmadian, Mohammad Ali Eghbal
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-12-01
Series:Pharmaceutical Sciences
Subjects:
Cytotoxicity
Drug-induced liver injury
Hepatotoxicity
Mitochondria
Oxidative stress
Antioxidants
Online Access:https://ps.tbzmed.ac.ir/PDF/PHARM_19891_20180501171214

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