Association between metabolic syndrome and Benign Prostatic Hyperplasia

• Main Authors: Raj Kumar Chhetri, Suman Baral
• Format: Article
• Language: English
• Published: Lumbini Medical College 2018-09-01
• Series: Journal of Lumbini Medical College
• Subjects: apple; ball; cat; doll; elephant
• Online Access: http://localhost/index.php/JLMC/article/view/207

Introduction: Metabolic syndrome defined as presence of atleast 3 of the following parameters: (1) waist circumference ≥90cm, (2) triglycerides >150 mg/dl or treatment for hypetriglyceridemia, (3) HDL-Co < 40 mg/dl or treatment for reduced HDL-C, (4) blood pressure ≥ 130/85 mmHg or current use of antihypertensive medications, (5) fasting blood glucose ≥110 mg/dl or previous diagnosis of type 2 diabetes mellitus, is closely associated with many diseases but recently studies are done to see its association with lower urinary tract symptoms and benign prostatic hyperplasia with varying results. Our study was targeted to investigate association between metabolic syndrome and benign prostatic hyperplasia. Methods: It was a prospective analytical study conducted among 104 patients age above fifty years with benign prostatic hyperplasia managed in the department of surgery of XXXXXXX Hospital over one year period. Results: Twenty-seven patients had metabolic syndrome (25.96%) and 93.2% had BMI < 25. With increase in age there was increase in mean prostate size though statistically not significant (P=0.759). Serum Triglyceride and HDL cholesterol were found to be positively correlating with the mean prostate size (P<0.05). There was increase in mean prostate size with increase in metabolic syndrome components which was statistically significant (P=0.0001). Metabolic syndrome was positively correlated with the mean prostate size. Conclusion: Serum Triglyceride and HDL cholesterol were found to be positively correlating with the mean prostate size (P<0.05). Metabolic syndrome was positively correlated with mean prostate size.