Large enchondroma of the thoracic spine: a rare case report and review of the literature

Abstract Background Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enc...

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Main Authors: Jing Guo, Ju-zhou Gao, Lian-jin Guo, Zhi-xun Yin, Er-xing He
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12891-017-1519-z
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spelling doaj-d16ddb8f8ae94a6ebb9e4e76ff7c52392020-11-25T00:46:07ZengBMCBMC Musculoskeletal Disorders1471-24742017-04-011811510.1186/s12891-017-1519-zLarge enchondroma of the thoracic spine: a rare case report and review of the literatureJing Guo0Ju-zhou Gao1Lian-jin Guo2Zhi-xun Yin3Er-xing He4Spine Surgery, The First Affiliated Hospital of Guangzhou Medical UniversitySpine Surgery, The First Affiliated Hospital of Guangzhou Medical UniversitySpine Surgery, The First Affiliated Hospital of Guangzhou Medical UniversitySpine Surgery, The First Affiliated Hospital of Guangzhou Medical UniversitySpine Surgery, The First Affiliated Hospital of Guangzhou Medical UniversityAbstract Background Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma in the thoracic spine of a 49-year-old woman, and discuss its clinical, radiological and histopathological characteristics. Case presentation The patient presented with rapidly progressive and severe pain on her upper back. Magnetic resonance imaging revealed an expansile lesion at the posterior elements of T3 that was hypointense on T1-weighted images and mixed iso- to hyperintense on T2-weighted images. Administration of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) resulted in heterogeneous enhancement. During surgery, a large tumor of 4.2cm × 4.7cm × 2.1cm was resected along with the lamina and spinous process. Histological examination revealed that the tumor consisted of mature hyaline cartilage with typical chondrocytes, indicating that it was an enchondroma. Conclusions Despite its benign-growing nature, enchondroma should be examined closely for signs of enchondromatosis and enchondrosarcoma. Complete surgical resection is the treatment of choice for immediate relief of symptoms and avoidance of recurrence.http://link.springer.com/article/10.1186/s12891-017-1519-zEnchondromaThoracic spineChondromaCase report
collection DOAJ
language English
format Article
sources DOAJ
author Jing Guo
Ju-zhou Gao
Lian-jin Guo
Zhi-xun Yin
Er-xing He
spellingShingle Jing Guo
Ju-zhou Gao
Lian-jin Guo
Zhi-xun Yin
Er-xing He
Large enchondroma of the thoracic spine: a rare case report and review of the literature
BMC Musculoskeletal Disorders
Enchondroma
Thoracic spine
Chondroma
Case report
author_facet Jing Guo
Ju-zhou Gao
Lian-jin Guo
Zhi-xun Yin
Er-xing He
author_sort Jing Guo
title Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_short Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_full Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_fullStr Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_full_unstemmed Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_sort large enchondroma of the thoracic spine: a rare case report and review of the literature
publisher BMC
series BMC Musculoskeletal Disorders
issn 1471-2474
publishDate 2017-04-01
description Abstract Background Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma in the thoracic spine of a 49-year-old woman, and discuss its clinical, radiological and histopathological characteristics. Case presentation The patient presented with rapidly progressive and severe pain on her upper back. Magnetic resonance imaging revealed an expansile lesion at the posterior elements of T3 that was hypointense on T1-weighted images and mixed iso- to hyperintense on T2-weighted images. Administration of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) resulted in heterogeneous enhancement. During surgery, a large tumor of 4.2cm × 4.7cm × 2.1cm was resected along with the lamina and spinous process. Histological examination revealed that the tumor consisted of mature hyaline cartilage with typical chondrocytes, indicating that it was an enchondroma. Conclusions Despite its benign-growing nature, enchondroma should be examined closely for signs of enchondromatosis and enchondrosarcoma. Complete surgical resection is the treatment of choice for immediate relief of symptoms and avoidance of recurrence.
topic Enchondroma
Thoracic spine
Chondroma
Case report
url http://link.springer.com/article/10.1186/s12891-017-1519-z
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