Case report: Treating a co-existence of hidradenitis suppurativa and psoriasis with different therapeutic approaches [version 2; peer review: 3 approved]

Hidradenitis suppurativa and psoriasis are considered chronic inflammatory diseases suggesting the existence of common pathogenetic pathways. We present two cases of comorbid psoriasis and hidradenitis suppurativa, treated with certolizumab pegol and brodalumab due to failure of response to other co...

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Bibliographic Details
Main Authors: Eleftheria Tampouratzi, Theodora Kanni, John Katsantonis, Theodora Douvali
Format: Article
Language:English
Published: F1000 Research Ltd 2020-12-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-2002/v2
Description
Summary:Hidradenitis suppurativa and psoriasis are considered chronic inflammatory diseases suggesting the existence of common pathogenetic pathways. We present two cases of comorbid psoriasis and hidradenitis suppurativa, treated with certolizumab pegol and brodalumab due to failure of response to other conventional therapies. Monoclonal antibody therapies have revolutionized the treatment of chronic inflammatory disorders such as psoriasis and hidradenitis suppurativa. Given the good clinical response to anti-IL-17 and anti-tumor necrosis factor agents in patients undergoing psoriasis and hidradenitis treatment, investigations on this direction could represent the starting point in new therapeutic approach for revolutionary treatment in these difficult-to-treat diseases.
ISSN:2046-1402