Differentiation and proliferation potencies of human bone tissue-derived mesenchymal stromal cells (hBT-MSCs) after long-term cryopreservation -Comparison among cells stored for 1, 5, 10, 15, and 20 years

Introduction: We investigated bone differentiation and proliferation potencies of human bone tissue-derived mesenchymal stromal cells (hBT-MSCs) after long-term cryopreservation. We determined the presence of any morphological and characteristic changes due to freezing to identify issues that need t...

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Bibliographic Details
Main Authors: Yoshika Sugimoto, Yasuharu Yamazaki, Kazuno Moriyama, Takayuki Sugimoto, Kenichi Kumazawa, Kyoko Baba, Yumiko Sone, Akira Takeda
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235232042100033X