SNGH16 regulates cell autophagy to promote Sorafenib Resistance through suppressing miR‐23b‐3p via sponging EGR1 in hepatocellular carcinoma

SNGH16 regulates cell autophagy to promote Sorafenib Resistance through suppressing miR‐23b‐3p via sponging EGR1 in hepatocellular carcinoma

Abstract Objective Tumor cells could acquire drug resistance through cell autophagy. This study aimed to explore the role of SNHG16 in sorafenib‐resistant HCC cells and its mechanism with miR‐23b‐3p. Methods The sorafenib‐resistant Hep3B cell model was established. The SNHG16 and miR‐23b‐3p gene exp...

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Bibliographic Details
Main Authors: Zhao Jing, Xiaoping Ye, Xiaojie Ma, Xiangrong Hu, Wenjun Yang, Junping Shi, Gongying Chen, Ling Gong
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Cancer Medicine
Subjects:
EGR1
hepatocellular carcinoma
MiR‐23b‐3p
SNHG16
sorafenib resistance
Online Access:https://doi.org/10.1002/cam4.3020

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