Increased conditioned place preference for cocaine in high anxiety-related behavior (HAB) mice is associated with an increased activation in the accumbens corridor

Increased conditioned place preference for cocaine in high anxiety-related behavior (HAB) mice is associated with an increased activation in the accumbens corridor

Anxiety disorders and substance use disorders are strongly associated in humans. Accordingly, a widely held but controversial concept in the addiction field, the so-called self-medication hypothesis, posits that anxious individuals are more vulnerable for drug dependence because they use drugs of ab...

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Bibliographic Details
Main Authors: Janine Maria Prast, Aurelia eSchardl, Simone B Sartori, Nicolas eSingewald, Alois eSaria, Gerald eZernig
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Anxiety
c-fos
Egr1
cocaine CPP
accumbens corridor
D1-MSNs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00441/full

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