β-Sitosterol increases mitochondrial electron transport by fluidizing mitochondrial membranes and enhances mitochondrial responsiveness to increasing energy demand by the induction of uncoupling in C2C12 myotubes
Mitochondrial bioenergetic adaptation is important for maintaining normal physiological functions, particularly in skeletal muscle, which displays a wide range of variations in energy demand. β-Sitosterol (BSS), an active component of Cistanches Herba, can influence mitochondrial membrane potential...
Main Authors: | Hoi Shan Wong, Pou Kuan Leong, Jihang Chen, Hoi Yan Leung, Wing Man Chan, Kam Ming Ko |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464616300093 |
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