SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes

SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes

Transforming growth factor-beta (TGF-β1) is a potent inductor of matrix metalloproteinase-9 (MMP-9) in transformed cells. Recently, Ski-interacting protein (SKIP) has been described as a regulator of TGF-β1 signal transduction, but its role in the induction of cell malignance by TGF-β1 has not been...

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Bibliographic Details
Main Authors:	Jelena Kocić, Victor Villar, Aleksandra Krstić, Juan F. Santibanez
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Scientifica
Online Access:	http://dx.doi.org/10.6064/2012/861647

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