Peroxisome Proliferator-Activated Receptor-γ Ligands Alter Breast Cancer Cell Motility through Modulation of the Plasminogen Activator System

We investigated peroxisome proliferator-activated receptor-γ (PPAR-γ) ligands effect on cell motility and the plasminogen activator system using normal MCF-10A and malignant MCF-10CA1 cell lines. Ciglitazone reduced both wound-induced migration and chemotaxis. However, the effect was not reversed wi...

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Bibliographic Details
Main Authors: Jennifer C. Carter, Frank C. Church
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2011/594258