Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-β1/Smad2/3 Signaling Pathway

Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-β1/Smad2/3 Signaling Pathway

Aim. Connexin 43 (Cx43) has been identified to be important for cerebral ischemia/reperfusion (I/R) injury as well as protection from it. This study was aimed at investigating the relationship between phosphorylated Cx43 (p-Cx43), transforming growth factor-β1 (TGF-β1)/Smad2/3 signaling pathway, and...

Full description

Bibliographic Details
Main Authors:	Jiangwen Yin, Xuejiao Liu, Ruixue Wang, Mingyue Ge, Liping Xie, Jingwen Zhai, Zhigang Dai, Yan Li, Sheng Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2020/3451215

Similar Items

Wnt/β-catenin signaling pathway contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury and is possibly related to the transforming growth factorβ1/Smad3 signaling pathway
by: Guixing Zhang, et al.
Published: (2019-02-01)

Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
by: Hossein Mostafavi, et al.
Published: (2014-02-01)

TGF-β2 Induces Gli1 in a Smad3-Dependent Manner Against Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats
by: Li Peng, et al.
Published: (2019-06-01)

Novel Functional Role of Heat Shock Protein 90 in Mitochondrial Connexin 43-Mediated Hypoxic Postconditioning
by: Rong-Hui Tu, et al.
Published: (2017-11-01)

Connexin43 hemichannel-mediated regulation of connexin43.
by: Kai Li, et al.
Published: (2013-01-01)

Connexin 43 Upregulation in Mouse Lungs during Ovalbumin-Induced Asthma.
by: Yin Yao, et al.
Published: (2015-01-01)

Fenofibrate Reduces the Asthma-Related Fibroblast-To-Myofibroblast Transition by TGF-Β/Smad2/3 Signaling Attenuation and Connexin 43-Dependent Phenotype Destabilization
by: Milena Paw, et al.
Published: (2018-08-01)

Resveratrol Sensitizes Colorectal Cancer Cells to Cetuximab by Connexin 43 Upregulation-Induced Akt Inhibition
by: Yijia Wang, et al.
Published: (2020-04-01)

Connexin 43 in osteogenesis
by: Krzysztof Łukowicz, et al.
Published: (2020-09-01)

Connexin 43 as a biological marker of ischaemia in occlusive arterial disease of the lower limb
by: Hussey, Keith Kelso
Published: (2018)

Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes
by: Haiyun Pei, et al.
Published: (2017-11-01)

Kanglaite sensitizes colorectal cancer cells to Taxol via NF-κΒ inhibition and connexin 43 upregulation
by: Yijia Wang, et al.
Published: (2017-04-01)

Function of Connexin-43 in Macrophages
by: Daniel Rodjakovic, et al.
Published: (2021-01-01)

Selectivity of Connexin43 and Connexin40 Comprised Gap Junctions
by: Heyman, Nathanael Stanlee
Published: (2007)

Connexin 43 Deficiency Is Associated with Reduced Myocardial Scar Size and Attenuated TGFβ1 Signaling after Transient Coronary Occlusion in Conditional Knock-Out Mice
by: Laura Valls-Lacalle, et al.
Published: (2020-04-01)

Coculture of Embryonic Ventricular Myocytes and Mouse Embryonic Stem Cell Enhance Intercellular Signaling by Upregulation of Connexin43
by: Hui Li, et al.
Published: (2013-07-01)

P6 Electroacupuncture Improved QTc Interval Prolongation by Upregulation of Connexin43 in Droperidol Treated Rats
by: Feng Zhao, et al.
Published: (2014-01-01)

Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium
by: Gillespie Mark N, et al.
Published: (2008-07-01)

The Role of Connexin 43 in Lung Disease
by: Julie A. Swartzendruber, et al.
Published: (2020-12-01)

The role of connexin43 in glioma motility
by: Bates, David Christopher
Published: (2010)

A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice
by: Hui Wang, et al.
Published: (2013-01-01)

Oscillating Pressure Treatment Upregulates Connexin43 Expression in Skeletal Myoblasts and Enhances Therapeutic Efficacy for Myocardial Infarction
by: Sae-Won Lee, et al.
Published: (2009-11-01)

Connexin 43 is Involved in Aldosterone-Induced Podocyte Injury
by: Min Yang, et al.
Published: (2014-11-01)

Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype
by: Anne-Cécile Boulay, et al.
Published: (2018-03-01)

The Importance of Connexin 43 in Enamel Development and Mineralization
by: Sali Al-Ansari, et al.
Published: (2018-06-01)

Dephosphorylation of Connexin43 Associated with Ventricular Hypertrophy
by: SASANO, Chieko, et al.
Published: (2002)

Connexin 43 impacts on mitochondrial potassium uptake
by: Kerstin eBoengler, et al.
Published: (2013-06-01)

Role of hypoxia in expression and localization of Connexin 43
by: Kavensky, Elisse
Published: (2016)

Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation
by: Shu-jie Wu, et al.
Published: (2020-02-01)

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways.
by: Saad Nazir, et al.
Published: (2015-01-01)

3,5,4′-tri-O-acetylresveratrol Ameliorates Seawater Exposure-Induced Lung Injury by Upregulating Connexin 43 Expression in Lung
by: Lijie Ma, et al.
Published: (2013-01-01)

Effect of celecoxib on the expression of connexin43 in retina of diabetic rats
by: Gui-Ping Pan, et al.
Published: (2018-06-01)

The expression of Cx43, TGFβ/Smads signaling pathway and PCNA in the occurence and development of gastric carcinoma and the relationship among them
by: Chun-Hui Li, et al.
Published: (2015-03-01)

Connexin 43 inhibits tumor growth by inducing autophagy
by: Man-Chin Chen, et al.
Published: (2014)

Role of Connexin 43 in an Inflammatory Model for TMJ Hyperalgesia
by: Fabeeha Ahmed, et al.
Published: (2021-08-01)

Connexin 43 peptidic medicine for glioblastoma stem cells
by: Zhi Sheng
Published: (2021-02-01)

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
by: Olga M. Rusiecka, et al.
Published: (2020-08-01)

Ouabain Modulates the Distribution of Connexin 43 in Epithelial Cells
by: Arturo Ponce, et al.
Published: (2016-09-01)

Antidepressants impact connexin 43 channel functions in astrocytes
by: Tiffany eJeanson, et al.
Published: (2016-01-01)

Connexin 43-Based Therapeutics for Dermal Wound Healing
by: Jade Montgomery, et al.
Published: (2018-06-01)

Cannot write session to /tmp/vufind_sessions/sess_0l62rjftaeu5vblmdpr225hefc