Synthesis of no-carrier-added [188, 189, 191Pt]cisplatin from a cyclotron produced 188, 189, 191PtCl4 2− complex
Abstract We developed a novel method for production of no-carrier-added (n.c.a.) [188, 189, 191Pt]PtIICl4 2− from an Ir target material, and then synthesized n.c.a. [*Pt]cis-[PtIICl2(NH3)2] ([*Pt]cisplatin) from [*Pt]PtIICl4 2−. [*Pt]PtIICl4 2− was prepared as a synthetic precursor of n.c.a. *Pt com...
Main Authors: | Honoka Obata, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-87576-2 |
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