Protective effects of Acyl-coA thioesterase 1 on diabetic heart via PPARα/PGC1α signaling.

Using fatty acids (FAs) exclusively for ATP generation was reported to contribute to the development of diabetic cardiomyopathy. We studied the role of substrate metabolism related genes in the heart of the diabetes to find out a novel therapeutic target for diabetic cardiomyopathy.By microarray ana...

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Bibliographic Details
Main Authors: Shenglan Yang, Chen Chen, Hong Wang, Xiaoquan Rao, Feng Wang, Quanlu Duan, Fuqiong Chen, Guangwen Long, Wei Gong, Ming-Hui Zou, Dao Wen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511550?pdf=render