The effect of vitamin K insufficiency on histological and structural properties of knee joints in aging mice

Summary: Objective: While a role for vitamin K in maintaining joint tissue homeostasis has been proposed based on the presence of vitamin K dependent proteins in cartilage and bone, it is not clear if low vitamin K intake is causally linked to joint tissue degeneration. To address this gap, we mani...

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Bibliographic Details
Main Authors: M. Kyla Shea, Sarah L. Booth, Stephanie G. Harshman, Donald Smith, Cathy S. Carlson, Lindsey Harper, Alexandra R. Armstrong, Min Fang, M. Leonor Cancela, Márcio Simão, Richard F. Loeser
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913120300698