TGF-β1 Promotes Osteosarcoma Cell Migration and Invasion Through the miR-143-Versican Pathway

Background & Aims: TGF-β1 is an abundant cytokine present in the tumour microenvironment. It has been shown to trigger versican expression in human osteosarcoma cells, which may account for the metastatic potential of these cells. However, the underlying mechanism of TGF-β1-mediated metastas...

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Bibliographic Details
Main Authors: Fengfeng Li, Shaohua Li, Tao Cheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/369660