A Smart Region-Growing Algorithm for Single-Neuron Segmentation From Confocal and 2-Photon Datasets

A Smart Region-Growing Algorithm for Single-Neuron Segmentation From Confocal and 2-Photon Datasets

Accurately digitizing the brain at the micro-scale is crucial for investigating brain structure-function relationships and documenting morphological alterations due to neuropathies. Here we present a new Smart Region Growing algorithm (SmRG) for the segmentation of single neurons in their intricate...

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Bibliographic Details
Main Authors: Alejandro Luis Callara, Chiara Magliaro, Arti Ahluwalia, Nicola Vanello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neuroinformatics
Subjects:
neuron segmentation
confocal microscopy
2 photon microscopy
expectation - maximization (EM) algorithm
mixture models
CLARITY
Online Access:https://www.frontiersin.org/article/10.3389/fninf.2020.00009/full

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