A glance at molecular mechanisms underlying cisplatin-induced nephrotoxicity and possible renoprotective strategies: a narrative review

A glance at molecular mechanisms underlying cisplatin-induced nephrotoxicity and possible renoprotective strategies: a narrative review

Cisplatin is a platinum-based drug that is usually used for the treatment of many carcinomas. However, it comes with several devastating side effects, including nephrotoxicity. Cisplatin toxicity is a very complex process, which is exacerbated by the accumulation of cisplatin in renal tubular cells...

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Bibliographic Details
Main Authors: Bashar Adi Wahyu Pandhita, Deliana Nur Ihsani Rahmi, Nielda Kezia Sumbung, Bernardino Matthew Waworuntu, Regina Puspa Utami, Melva Louisa, Vivian Soetikno
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2019-10-01
Series:Medical Journal of Indonesia
Subjects:
cisplatin
kidney
kidney injury
oxidative stress
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/2690

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