Mathematical modelling of cancer invasion: The role of membrane-bound matrix metalloproteinases
One of the hallmarks of cancer growth and metastatic spread is the process of local invasion of the surrounding tissue. Cancer cells achieve protease- dependent invasion by the secretion of enzymes involved in proteolysis. These overly-expressed proteolytic enzymes then proceed to degrade the host t...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-04-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00070/full |