Association of TPMT (rs1800460) Gene Polymorphism with Childhood Acute Lymphoblastic Leukemia in a Population from Guilan, Iran

Acute lymphoblastic leukemia (ALL) is a malignant transformation and proliferation of lymphoid progenitor cells in bone marrow and blood, which is mainly found in children. Thiopurine methyltransferase (TPMT) is a thiopurine drug metabolizer enzyme that is prescribed for the treatment of ALL. Severa...

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Bibliographic Details
Main Authors: Mohammad Hedayati, Hamidreza Vaziri, Bahram Darbandi, Adel Baghersalimi, Mohammadmahdi Jafarzadeh, Ali Salehzadeh
Format: Article
Language:English
Published: University of Mazandaran 2020-09-01
Series:Journal of Genetic Resources
Subjects:
Online Access:http://sc.journals.umz.ac.ir/article_2789_8dcb6cf9adb5f67063ab194b857b9992.pdf