Finding the Keys to the CAR: Identifying Novel Target Antigens for T Cell Redirection Immunotherapies

Finding the Keys to the CAR: Identifying Novel Target Antigens for T Cell Redirection Immunotherapies

Oncology immunotherapy has been a significant advancement in cancer treatment and involves harnessing and redirecting a patient’s immune response towards their own tumour. Specific recognition and elimination of tumour cells was first proposed over a century ago with Paul Erlich’...

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Bibliographic Details
Main Authors: Rebecca C. Abbott, Ryan S. Cross, Misty R. Jenkins
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
chimeric antigen receptor t cells (car t)
bi-specific t cell engager (bite)
immunotherapy
oncology
antigen selection
target antigen
proteomics
glycomics
lipidomics
antigenic screen
cell surface antigen
phage display
Online Access:https://www.mdpi.com/1422-0067/21/2/515

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