N6-Methyladenosine RNA Modification in Inflammation: Roles, Mechanisms, and Applications

N6-Methyladenosine RNA Modification in Inflammation: Roles, Mechanisms, and Applications

N6-methyladenosine (m6A) is the most prevalent internal mRNA modification. m6A can be installed by the methyltransferase complex and removed by demethylases, which are involved in regulating post-transcriptional expression of target genes. RNA methylation is linked to various inflammatory states, in...

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Bibliographic Details
Main Authors: Jiahui Luo, Tao Xu, Kai Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
N6-methyladenosine
RNA modification
epigenetics
inflammation
inflammatory disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.670711/full

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