Soluble amyloid-b oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

Soluble amyloid-b oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia in the elderly, and affects millions of people worldwide. As the number of AD cases continues to increase in both developed and developing countries, finding therapies that effectively halt or reverse disease progression constitutes a majo...

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Bibliographic Details
Main Authors: Sergio T. Ferreira, Mychael V. Lourenco, Mauricio M. Oliveira, Fernanda G. De Felice
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
memory loss
Alzheimer’s disease
amyloid-b oligomers
Neuronal dysfunction
synapse failure
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00191/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00191/full

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