Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

Decrease in fibroblast-produced collagen has been proven to be the pivotal cause of skin aging, but there is no satisfactory drug which directly increases dermal thickness and collage density. Here we found that a flavonoid natural product, apigenin, could significantly increase collagen synthesis....

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Bibliographic Details
Main Authors: Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li
Format: Article
Language:English
Published: PAGEPress Publications 2015-04-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://ejh.it/index.php/ejh/article/view/2467