One-pot synthesis of cyanohydrin derivatives from alkyl bromides via incorporation of two one-carbon components by consecutive radical/ionic reactions
The consecutive radical/ionic reaction consisting of radical formylation of alkyl bromides and nucleophilic addition of a cyanide ion was investigated, which gave moderate to good yields of cyanohydrin derivatives in one-pot.
Main Authors: | Shuhei Sumino, Akira Fusano, Hiroyuki Okai, Takahide Fukuyama, Ilhyong Ryu |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2014-01-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.10.12 |
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