Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase.

Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase.

Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the Polycomb-repressive complex 2 (PRC2) that epigenetically silences gene transcription through histone H3 lysine trimethylation (H3K27me3). EZH2 has been implicated in stem cell maintenance and is overexpressed in hematological and sol...

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Bibliographic Details
Main Authors: Martina Ott, Ulrike M Litzenburger, Felix Sahm, Katharina J Rauschenbach, Ruxandra Tudoran, Christian Hartmann, Victor E Marquez, Andreas von Deimling, Wolfgang Wick, Michael Platten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471855?pdf=render

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http://europepmc.org/articles/PMC3471855?pdf=render

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