Stability assessment of Lanette Lotion of a magistral pharmacy in the region of Curitiba

• Main Authors: A. C. Santos, B. K. Souza, A. F. T. Souza, N. C. Lubi, T. F. B. X. Silva
• Format: Article
• Language: English
• Published: Universidade Federal de Rondonópolis 2020-04-01
• Series: Scientific Electronic Archives
• Subjects: lotion lanette, stability assessment, base stability
• Online Access: https://sea.ufr.edu.br/index.php?journal=SEA&page=article&op=view&path=913

Emulsions are heterogeneous systems, thermodynamically unstable, formed by the combination of hydrophilic and lipophilic substances through agents of surface tension. The product quality control is handled as the most important to study the stability of the final product which determines the length of time that can be considered stable, that means, able to keep up with the same characteristics which have been developed. The study aimed to evaluate the physical and chemical parameters, by determining the pH, viscosity and organoleptic characteristics (color, odor and appearance) of the lotion Lanette used in a magistral pharmacy in Curitiba. The formulation commonly used in the pharmacy was stored at temperatures of 4 ° C ambient and 45 ° C over a period of 90 days which was divided into 6 times to carry out aspects of analysis. In the preliminary stability study there was no change, but in the accelerated there was a slight modification in appearance, this change was more intense in the formulation conditioned at room temperature and 4 ° C. The pH has had a significant change at all temperatures. Concluding that against accelerated stability tests Lanette lotion, even with the changes, showed good stability.