Acute poisoning with herbicide glyphosate

• Main Authors: Vukotić Milidrag, Paleksić Vesna, Narić Slaviša
• Format: Article
• Language: English
• Published: Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine 2018-01-01
• Series: Scripta Medica
• Subjects: glyphosate; acute poisoning; enzymes; safety and health
• Online Access: https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2018/2490-33291802141V.pdf

Glyphosate is the most common used organophosphorus herbicide which most probably inhibits oxidative phosphorylation without leading to the inhibition of esterases. Glyphosate poisoning is mostly the consequence of the synergistic effect of an active substance and surfactant. There is a case of 42-year-old patient who worked on weed spraying with glyphosate, with hand sprinkler. Symptoms of the acute poisoning such as weakness, sweating, nausea, vomiting and stomach ache were visible right after the working period. With biochemical analysis increased activity of the enzymes AST, ALT and y-GT were diagnosed and sanated after aborting an expositions in the period of six months and treatment. In this shown case poisoning was caused during applying herbicides without proper handling with the herbicide and also because of non-compliance of measures in safety and health at work. It is very clear that this is a case of acute poisoning with pesticides which ended with no consequences and was declared as work injury.